Proteotoxic stress as a driver of MDS stem cell expansion.

2025

Overview

The Vera and Joseph Dresner Foundation granted Childrens Hospital Medical Center a $500,000 grant over two years for established investigator Dr. Timothy M. Chlon.

Details

In this project, Dr. Chlon will test his theory whether increased protein misfolding promotes mutant stem cell expansion and then test the effect of drugs that reduce protein stress to prevent this expansion.

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